O’Keeffe’s Working Hands Hand Cream is a concentrated hand cream that heals, relieves and repairs extremely dry, cracked hands. When used daily, O’Keeffe’s Working Hands is clinically proven to instantly boost moisture levels, creates a protective layer on the skins surface, and help prevent further moisture loss. It is safe and effective for people with diabetes. Why does O'Keeffe's work? The skin's natural barrier can be damaged, causing dry, cracked skin. O'Keeffe's Working Hands contains a high concentration of glycerine that draws in and retains moisture, which is necessary for healthy skin and creates a protective barrier on the skin's surface that locks in moisture, keeps your skin hydrated, and helps relieve hand dryness. Before and After Hand Images are after a one-week usage period. Cream was applied before bed and three time's day. Results may vary.